Articles

Call to Action: Greater Focus on Metastatic Cancer Survivors Is Needed
Two cancer experts at Johns Hopkins Kimmel Cancer Center in Baltimore, MD, are advocating for greater focus on metastatic cancer survivorship and its impact on those living with incurable cancer, a situation they know all too well. Both are living with metastatic cancer and are urging the medical community to increase the study and awareness of this condition and improve the lives of this growing population. Read More ›

Studies Show ACA Reduces Disparities and Increases Access to Earlier Diagnosis and Treatment
Chicago, IL—Results from a new clinical trial suggest that limited access to care is the main contributing factor to the disparities in outcomes that exist between African American patients and white patients with cancer. Read More ›

Lung cancer is the second most frequently diagnosed malignancy in both men and women (following prostate and breast cancer, respectively), and the leading cause of cancer deaths overall. Non–small-cell lung cancer (NSCLC) is the most common type, with the more aggressive small-cell lung cancer (SCLC) making up approximately 10% to 15% of cases. Read More ›

From the Editor - TON June 2019
The June issue of The Oncology Nurse-APN/PA (TON) is filled with important news and insights for today’s oncology nurse. We begin our coverage with a profile of the Massachusetts General Hospital Cancer Center, Boston, as we speak with Kathryn E. Post, PhD, RN, ANP-BC, Clinical Oncology Nurse Practitioner, Breast Oncology Group, and Postdoctoral Research Fellow, Cancer Outcomes Research Program, who discussed her dual roles at the center, some of the challenges she faces in her profession, and what she finds exciting in the evolving field of oncology. Read More ›

The Massachusetts General Hospital Cancer Center is an integral part of one of the most distinguished academic medical centers in the United States: Massachusetts General Hospital, Boston. The institution offers personalized innovative treatments to adults and children with cancer through >37 programs within 29 multidisciplinary disease centers plus a vast array of support and educational services in New England and the southeastern United States. It also has one of the largest hospital-based research programs in the country. Its physician investigators conduct nearly 400 clinical trials annually, and its nurses were the first in Massachusetts to achieve Magnet status from the American Nurses Credentialing Center in recognition of the excellent care they provide to patients. Read More ›

Assessment of Opioid Misuse and Abuse Should Be Part of Cancer Pain Management
Orlando, FL—Maintaining patient safety and minimizing the risks for opioid misuse and abuse in the management of cancer pain require proper assessment and new strategies for pain management that include integrative interventions, according to Judith A. Paice, PhD, RN, Director, Cancer Pain Program, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL. She discussed this topic at the 2019 National Comprehensive Cancer Network (NCCN) Conference. Read More ›

First Positive Showing for Mesothelin-Directed CAR T-Cell Therapy in Solid Tumors
Atlanta, GA—Chimeric antigen receptor (CAR) T-cell therapy has had dramatic results in hematologic malignancies, but so far, getting CAR T-cells to work in solid tumors has proved elusive. That may be about to change if promising results from a phase 1 clinical trial are confirmed by further studies. The results of this pivotal study were presented at the 2019 American Association for Cancer Research (AACR) annual meeting. Read More ›

Expert Panel Discusses Access to CAR T-Cell Therapy
Orlando, FL—With price tags approaching $1 million or more for delivery of certain immune cell therapies, new payment models will be needed to ensure access to these therapies and to further innovations. This was a key issue addressed at a roundtable discussion at the 2019 National Comprehensive Cancer Network (NCCN) Conference. Ensuring access to chimeric antigen receptor (CAR) T-cell therapy emerged as a top area of concern. Read More ›


Osimertinib plus Savolitinib Promising for Non–Small-Cell Lung Cancer with MET-Driven Resistance
Atlanta, GA—The combination of the investigational MET inhibitor savolitinib plus the EGFR inhibitor osimertinib (Tagrisso) achieved encouraging responses in patients with MET-amplified, EGFR-positive non–small-cell lung cancer (NSCLC) and acquired, MET-driven resistance to previous therapies, with an acceptable side-effect profile. These findings represent interim results of 2 expansion cohorts of a phase 1b clinical trial presented at the 2019 American Association for Cancer Research meeting. Read More ›

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