Articles

Findings of the multicohort phase 1 TRIMM-2 trial showed that the G-protein–coupled receptor family C group 5 member D x CD3 bispecific antibody talqueta­mab in combination with daratumumab therapy was well-tolerated and resulted in promising antitumor activity in patients with RRMM, supporting further evaluation of this combination. Read More ›

The chemistry behind selective KRAS G12C therapies and potential future research avenues were discussed in a recently released journal article. Read More ›

In a recent study, researchers identified several factors associated with the development of pneumonitis with therapies targeting non–small-cell lung cancer. Read More ›

Considerations in first-line and second-line therapy selection in non–small-cell lung cancer without genetic alterations were presented in a recent review article. Read More ›

Although generally mild adverse events are associated with the use of immune checkpoint inhibitors for non–small-cell lung cancer, occasionally serious complications may result. Read More ›

From The Editors February 2022
The February issue of The Oncology Nurse-APN/PA (TON) features a variety of articles that specifically address topics of interest for nurses, navigators, and advanced practice providers caring for patients with cancer, including the latest results from clinical trials evaluating novel and FDA-approved therapies being used to extend survival and enhance quality of life. Read More ›

As the COVID-19 pandemic continues into 2022, advocacy groups have worked tirelessly to provide vital services to patients with cancer while facing numerous challenges, including reductions in staff and decreased funding. Read More ›

The results from 2 phase 3 clinical trials highlighted the superiority of CAR T-cell therapies over current standard of care (SOC) when used earlier in the course of treatment for patients with large B-cell lymphoma (LBCL). Read More ›

The use of telehealth in the fee-for-service program surged by more than 4000% during the first 6 months aof the COVID-19 pandemic. Read More ›

Second-line therapy with trastuzumab deruxtecan (Enhertu; T-DXd) extended progression-free survival (PFS) and improved objective response rate (ORR) versus trastuzumab emtansine (Kadcyla; T-DM1) in women with HER2-positive metastatic breast cancer, including those with stable brain metastasis at baseline, according to a subgroup analysis of a phase 3 clinical trial. Read More ›

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