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ASCO 2021 - Breast Cancer

Moderate physical activity reduced the inflammatory response triggered by neoadjuvant chemotherapy in breast cancer patients prior to surgery. The benefit appears to be lost after surgery.
Diverse factors contribute to shifts in psychosocial function in breast cancer patients after treatment. Understanding these factors provides opportunities for patients to receive more holistic care.
Actionable biomarkers associated with directed treatment to prevent or reverse symptoms in African Americans with advanced-stage breast cancer may reduce mortality rates.
The SOLAR-1 and X2101 trials demonstrate long-term disease control can be attained for ≥18 months with alpelisib plus fulvestrant in patients with hard-to-treat HR-positive/HER2-negative advanced breast cancer.
Many women with HR-positive breast cancer contend with emotional distress during prolonged adjuvant endocrine therapy. Behavioral interventions show promise as effective strategies to reduce stress and improve adherence to therapy.
Telehealth visits provide increased access to care for oncology patients across multiple demographics with reported high patient satisfaction with level of care.
Low socioeconomic status is associated with delayed access to age-appropriate cancer screenings due to cost of care.
Perceived fatigability may be a more clinically relevant measurement of the effectiveness of exercise intervention on reducing fatigue among survivors of breast cancer.
Advanced-stage diagnosis of breast cancer is associated with deprived-rural socioeconomic status in French women.
Alpelisib may overcome resistance to CDK4/6 inhibitors in HR-positive/HER2-negative advanced breast cancer patients with shorter exposure to prior CDK4/6 inhibitor treatment.
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