Articles

Although management of lymphoma during pregnancy is not well studied, a retrospective review at 10 academic centers in the United States suggests that in selected cases, lymphoma can be treated with minimal maternal and fetal complications, and that treatment can be deferred until after giving birth in patients with low-risk lymphomas. The study was presented at the 53rd Annual Meeting of the American Society of Hematology held December 2011 in San Diego, California.

It is one of the most contentious issues in U.S. politics today: the federal health-care law’s requirement that everybody have health insurance or pay a penalty.

Supporters of the mandate—which is the central issue in the case before the Supreme Court challenging the law—argue that it’s the key to making health care more affordable and accessible to everyone. By expanding the pool of insured, the thinking goes, the burden of paying for the sick is covered by all.

In a randomized phase 2 study of patients with metastatic breast cancer, peripheral neuropathy was less likely to occur in patients receiving eribulin mesylate than with ixabepilone.

“Peripheral neuropathy is a big problem in the treatment of breast cancer. Across the spectrum, patients have it, and we don’t know how to treat it,” said Linda T. Vahdat, MD, Weill Cornell Medical College in New York, who presented the study at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium.

A quality-of-life analysis of the large randomized NCIC MA. 27 trial shows that symptoms of endocrine therapy can be severe and have a negative effect on quality of life. The study also found that women with side effects from previous chemotherapy or radiotherapy before they start taking endocrine therapy are at higher risk for early discontinuation.

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Take the chill out of winter with the nutrient-packed goodness of lentils. These tiny members of the legume family may be small in size but are big on nutrition. Lentils are loaded with vitamins, minerals, fiber, and protein. They also contain antioxidants and phytonutrients—naturally occurring plant compounds that help prevent damage to cells throughout the body. Lentils are so versatile that they can be made into a variety of different dishes, from appetizers and side dishes to main meals and desserts.

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In 2011, the American Cancer Society projected there would be 20,520 cases of newly diagnosed multiple myeloma (MM) and 10,610 deaths from the disease that year.¹ MM is an incurable hematologic cancer marked by great heterogeneity, in terms of its biology and clinical course. Morbidity and survival rates vary widely, even in the age of novel, molecularly based targeted therapies. Many factors account for differences in prognoses among patients with MM, including genomic aberrations in the plasma cells of the myeloma neoplasm. Read More ›

Recent economic challenges resulted in cutbacks in personal healthcare spending among continuously insured Americans, according to researchers at the University of North Carolina (UNC) at Chapel Hill School of Medicine. These insured patients underwent fewer screening colonoscopies, a cost-effective, recommended preventive service, during the recession.

The study appears in the March issue of the journal Clinical Gastroenterology and Hepatology.

Researchers have found that a new drug for metastatic melanoma nearly doubles the median survival time for patients with a common genetic mutation.

The data come from an international phase 2 study of the drug Zelboraf (vemurafenib). More than half of the 132 patients who were treated with the novel agent responded to treatment and experienced a median overall survival of almost 16 months. Patients with this advanced form of melanoma, in which the cancer has spread to other organs, typically survive about 9 months.

The new healthcare law’s Preexisting Condition Insurance Plan (PCIP) program is providing insurance to thousands of people with high-risk preexisting conditions. The US Department of Health and Human Services recently reported how PCIP is helping to fill a void in the insurance market.