Articles

When combined, 6 common, recognized radiotherapy safety checks cut potential patient-harming errors by 90%, according to a new study led by Johns Hopkins researchers. 

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Late-stage ovarian cancer patients responded well to an experimental carboplatin/decitabine combination therapy, even though they had become resistant to carboplatin, Indiana University researchers report. Furthermore, the researchers believe they have discovered biomarkers that could assist in identifying patients who are most likely to benefit from this therapy. 

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New breast cancer screening guidelines recommend mammography screening annually for women beginning at age 40. The American College of Obstetricians and Gynecologists (ACOG) believes that the high incidence of breast cancer combined with the potential to reduce deaths from it when caught early warrants this change from its previous recommendations (every 1-2 years starting at age 40; annually beginning at age 50).

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Although maspin is believed to reduce the formation, development, and spread of tumors in several aggressive cancers (breast, ovarian, and head and neck cancers), it has been challenging to utilize this information and predict how cancer patients will fare with its use; the presence of maspin has been associated with both good and bad prognoses. The cause of this irregularity was considered to be based on the location of maspin within the cell, whether in the nucleus or in the cytoplasm, according to Drs. Read More ›


In young women with early-stage breast cancer, coupling the GnRH analogue triptorelin with chemotherapy led to a 17% reduction in the occurrence of early menopause, according to a report in the July 20 issue of JAMA.

The phase 3 study results showed:

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Medical oncologists and primary care physicians (PCPs) expressed major differences in knowledge, attitudes, and practices required to care for America's 12 million cancer survivors, according to a recent study published online in the Journal of General Internal Medicine.

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Patients with HER2+ breast cancer who develop resistance to trastuzumab may soon have an alternative therapy, according to recent findings published in Clinical Cancer Research.

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Maintaining a healthy body weight is important for all patients. But, this is especially true for women with a breast cancer diagnosis, as an analysis of the California Teachers Study has shown a correlation between breast cancer deaths and body mass index (BMI).

Obesity (defined as BMI ≥30 kg/m²) increased a woman’s risk of dying of their breast cancer by 69%, compared with women with a BMI <25. For patients who were overweight at 18 years of age (defined as BMI 25-29), a similar increased risk in breast cancer mortality was detected.

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Short-term androgen-deprivation therapy (ADT) for 4 months before and during radiotherapy increases overall survival rates and decreases disease-specific mortality rates in men with intermediate-risk prostate cancer, according to an interventional phase 3 study.

 

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Continuous use of aspirin for 5 years or more reduces the risk of cutaneous melanoma by almost half, according to results of a case-control study. Continuous use of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) also reduces risk, but only by 25%.

 

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