Hematologic Cancers

The advent of imatinib (Gleevec; Novartis Pharmaceuticals) was considered a near miracle for the treatment of chronic myeloid leukemia (CML). Read More ›

Routine surveillance imaging of asymptomatic patients in first remission after treatment for diffuse large B-cell lymphoma offers little clinical benefit at substantial cost, according to Scott F. Huntington, MD, of Abramson Cancer Center, University of Pennsylvania, Philadelphia, and colleagues. Read More ›

Ibrutinib represents a major advance in the treatment of previously treated chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), having achieved dramatic and sometimes durable responses in both diseases. Although ibrutinib is approved by the US Food and Drug Administration for both CLL and MCL, judging by the show of hands at the Oncology Nursing Society 39th Annual Congress, the majority of oncology nurses have not yet had experience with it. Read More ›

Imagine you’ve been feeling more tired lately, but you think, who isn’t? You work long hours at the office and at home. The fatigue becomes worse. After a battery of blood tests, the practitioner tells you the results. Read More ›

Several new drugs for the treatment of chronic lymphocytic leukemia (CLL) are considered major advances: 2 have been approved and 2 are under review by the US Food and Drug Administration (FDA). Read More ›

The optimal dosing of pomalidomide in the treatment of multiple myeloma has not been established. Yale University investigators compared continuous and intermittent dosing regimens, and while the intermittent schedule was associated with more toxicity, they concluded that it is preferable... Read More ›

For patients with non-Hodgkin lymphoma (NHL) receiving chemotherapy, primary prophylaxis against febrile neutropenia (FN) can safely be administered on the same treatment day, if necessary, according to a review of patients from the Cleveland Clinic, presented at the 2013 American Society of Hematology annual meeting. Read More ›

As the second leading cause of cancer-related deaths among men in the United States, prostate cancer is expected to cause approximately 29,720 deaths during 2013. In recognition of National Prostate Cancer Awareness Month, let’s examine these prostate cancer statistics. Read More ›

Advances in the understanding of the biology of multiple myeloma (MM) and the identification of new drugs have resulted in improved management of MM, including patients who are refractory to proteasome inhibitors and immunomodulatory agents. Read More ›

This article discusses ongoing clinical investigations of the agent in a wide range of therapeutic areas. Read More ›