TON - May 2018, Vol 11, No 2

The Oncology Nurse-APN/PA spoke with Salimah H. Meghani, PhD, MBE, RN, FAAN, a faculty member at the University of Pennsylvania School of Nursing, Philadelphia, about her various roles and thoughts on what is exciting in the field of palliative care.

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AONN+ Takes a Seat at the Table for the Biden Cancer Initiative

The Academy of Oncology Nurse & Patient Navigators had a strong presence at the first of the Biden Cancer Initiative’s “Conversation with Dr Biden,” on March 10, 2018. These conversations provide members of the patient support network with the opportunity to share their perspectives on the cancer journey.

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Suboptimal Dosing of Filgrastim is Acceptable for Treatment of Chemotherapy-Induced Neutropenia

Based on research presented at the 2018 National Comprehensive Cancer Network Annual Conference, patients weighing 60 kg to 85 kg who often receive lower-than-recommended doses of filgrastim, without evidence of its noninferiority to recommended doses, is found to be not only acceptable, but also cost-saving.

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From the Editor - TON May 2018

The May issue of The Oncology Nurse-APN/PA (TON) is full of important news and updates for oncology nurses.

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Immunotherapy Combination Shows Promising Results in HER2 1+/2+ Breast Cancer

Interim data from a recent clinical trial of nelipepimut-S plus trastuzumab showed a disease-free survival advantage compared with trastuzumab alone in patients with HER2 1+/2+ breast cancer.

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Chlamydia Trachomatis Infection Doubles the Risk for Ovarian Cancer

In 2 independent studies presented at the 2018 American Association for Cancer Research Annual Meeting, chlamydia trachomatis infection was shown to increase the risk for developing ovarian cancer by approximately 2-fold.

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Immunotherapy Plus Targeted Therapy Combination Active in Metastatic CRC

“The combination of atezolizumab and cobimetinib represents the first potential immune-modifying combination for patients with microsatellite stable metastatic colorectal cancer,” said Johanna C. Bendell, MD, at the 2018 Gastrointestinal Cancers Symposium.

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Understanding the Need for New Treatment Strategies for Infants with Acute Lymphoblastic Leukemia

Paige Johnson, DNP, CPNP, CPHON, discusses some of the characteristics that contribute to poor prognosis in infants with acute lymphoblastic leukemia, the results of clinical trials evaluating newer therapies to treat the disease, and what the future holds in terms of novel strategies.

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FDA News - May 2018

Adjuvant Chemotherapy in Upper-Tract Urothelial Cancer Shows Impressive Gains in the POUT Trial

At the 2018 Genitourinary Cancers Symposium, lead investigator Alison Jane Birtle, MD, MBBS, MRCP, FRCR, presented the results of the phase 3 POUT clinical trial, which showed that adjuvant chemotherapy had impressive gains in the disease-free survival and metastasis-free survival in upper-tract urothelial cancer

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