Web Exclusives

The article by Dr Hansen provides a great overview of the challenges facing patients from initial diagnosis of cancer through survivorship. Patients typically are diagnosed with cancer suddenly in the midst of living their lives. The various stressors in life that exist prior to diagnosis can be further exacerbated after diagnosis. As oncology providers, in addition to having knowledge of the options to treat a patient’s cancer, we need to make sure we understand the patient as a whole— both the patient and the person.

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The diagnosis of cancer is arguably one of the most emotionally exhausting and potentially psychologically debilitating medical conditions we may experience during our lifetime. However, the impact of this diagnosis is not limited to the patient and frequently resonates among family members, friends, and caregivers as well. When the impact of cancer on the human condition is combined with the knowledge that healthcare practitioners are frequently unable to detect psychological distress in this patient population, the effects can be profound.1

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New research shows that breast cancer survivors may face problems with cognitive abilities several years after therapy, regardless of whether they received chemotherapy plus radiation or radiation only. The study, published early online in Cancer, indicates possible common and treatment-specific ways in which cancer treatments negatively affect cancer survivors’ cognitive skills.

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ADCETRIS™ (brentuximab vedotin), a new CD30-directed antibody-drug conjugate (ADC), was approved by the U.S. Food and Drug Administration (FDA) on August 19, 2011, for the treatment of patients with relapsed or refractory Hodgkin lymphoma (HL) after failure of autologous stem cell transplant (ASCT) or after failure of at least 2 prior multiagent chemotherapy regimens. ADCETRIS is also indicated for the treatment of patients with systemic anaplastic large cell lymphoma (ALCL) after failure of at least 1 prior multiagent chemotherapy regimen.1

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In the September issue, we published an editorial entitled “I Am a Nurse Practitioner, NOT a Mid-Level Provider,” in which author Alison Moriarty Daley provided an argument against this phrase. We asked our online reading community what they think about “mid-level provider.”

  • 17% accepted mid-level provider as an accurate term
  • 50%agreed with Ms Daley that it is an insult
  • 33% didn’t think it mattered since nobody knows what the term means
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BOSTON—As more targeted therapies for non–small-cell lung cancer (NSCLC) become available, experts are assessing which patients’ tumors should be genotyped and when. Although genotyping—not to be confused with genetic testing—is becoming increasingly important in developing a treatment plan, professional guidelines do not yet recommend incorporating it as a routine part of care for patients with NSCLC.

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Patients with HER2+ breast cancer who develop resistance to trastuzumab may soon have an alternative therapy, according to recent findings published in Clinical Cancer Research. This therapy involves HER2-Affitoxin, a protein that combines HER2-specific affibody molecules and a modified bacterial toxin, PE38, according to study investigator Jacek Capala, PhD, DSc, of the National Cancer Institute. Read More ›


A recently developed urine test can assist in the early detection of and treatment decisions regarding prostate cancer, a study from the University of Michigan Comprehensive Cancer Center and the Michigan Center for Translational Pathology finds.

Designed to supplement an elevated prostate-specific antigen (PSA) screening result, this test also defines men at highest risk for clinically significant prostate cancer and could delay or negate the need for a needle biopsy in some patients.

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BOSTON—The national discourse on cancer screening has come a long way since 1988, when Ronald Reagan became the first president to say “breast cancer” in public, noted Alec Stone, MA, MPA, Health Policy Director, Oncology Nursing Society (ONS). After the US Preventive Services Task Force (USPSTF) recommended mammography screening every 2 years instead of annually, beginning at 50 years of age instead of 40, the public outcry was widespread and loud. Controversy has also been swirling about prostate cancer screening recommendations.

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