Cancer that originates in the liver is known as primary liver cancer.1,2 According to the American Cancer Society, approximately 41,260 individuals (28,600 men and 12,660 women) will be diagnosed with primary liver cancer in the United States in 2022, and approximately 30,520 individuals (20,420 men and 10,100 women) will die from the disease.2 From 1980 to 2015, incidence rates for primary liver cancer have more than tripled, although these rates have stabilized recently, and between 1980 and 2013, the overall liver cancer death rate has more than doubled.2,3 How much do you know about primary liver cancer?
Primary liver cancer can occur in both adults and children. However, treatment approaches for children are different than those for adults.1 The most common types of primary liver cancers in adults are hepatocellular carcinoma and intrahepatic cholangiocarcinoma (bile duct cancer), comprising approximately 75% and 10% to 20% of cases, respectively.2,3 The 5-year overall survival rate for primary liver cancer and intrahepatic cholangiocarcinoma for all stages combined is 20%; 35% for localized disease, 12% for regional disease, and 3% for distant disease.2,3 Public awareness of primary liver cancer needs to become a priority to improve diagnosis, treatment, and patient outcomes.
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