Articles

Today, plastic surgery has achieved great strides in restoring appearance and function.¹ In patients with cancer, reconstructive surgery must allow for adequate resection of tumor with clear margins, facilitate initiation of adjuvant therapy, and maximize quality of life by making the most of function and esthetics. Read More ›

Axillary Lymph Node Dissection Unnecessary for Some Early-Stage Breast Cancer Patients

By Christin Melton

TON - Daily

Data published in the Journal of the American Medical Association last week indicate that for 20% of women with early-stage breast cancer, removing malignant lymph nodes from the armpit does not improve survival or prevent recurrence. As expected, women in the phase III trial who underwent complete axillary lymph node dissection (ALND) had higher rates of lymphedema than those who had sentinel lymph node dissection (SLND) alone (P <.001). Read More ›

FDA Panel Recommends Stricter Process for Accelerated Approval of Cancer Drugs

By Christin Melton

TON - Daily

The FDA held a public meeting on Tuesday to assess whether stricter criteria are needed when considering oncology drugs for accelerated approval. Measures enacted in 1992 allow the FDA to grant accelerated approval for drugs targeted at unmet needs in cancer based solely on data from single-arm studies and relying on endpoints other than the standard metric of overall survival. Read More ›

Molecular Markers Help Identify Men with High-Risk Prostate Cancer

TON - Daily

A newly discovered four-gene signature might someday be used to help clinicians distinguish between indolent and aggressive prostate cancer at diagnosis and end the ongoing debate over immediate versus delayed treatment. “The vast majority of prostate cancers would not become life-threatening, even if left untreated. Read More ›

New Copay Program for Granisetron

TON - Daily

Patients can instantly save up to $200 off their copay with each prescription for PediatRx’s Granisol, the only FDA-approved ready-to-use liquid solution of granisetron. This new copay assistance program also leverages technology to initiate prior approval if a patient’s insurance requires it.

TON - Daily

Women may be at greater risk for breast cancer if they start hormonal therapy before or soon after menopause, according to a large prospective study. Women who begin therapy 5 or more years after menopause are at less risk.

TON - Daily

By training men with prostate cancer scheduled for prostatectomy on stress management techniques, nurses can help them raise their immune outcome and lower their mood disturbance. These outcomes, identified in a randomized study, build on the previous discovery that stress management techniques can improve quality of life 1 year postsurgery.

TON - Daily

Avoiding intermittent high-dose dexamethasone (HD) when administering the vincristine/doxorubicin/dexamethasone (VAD) regimen can reduce the risk for bacterial infection in patients with multiple myeloma (MM), suggest the results of a Japanese study published in the January issue of the International Journal of Hematology.

TON - Daily

The US Food and Drug Administration has approved rituximab (Rituxan, Genentech/Biogen Idec) for maintenance treatment for patients with advanced follicular lymphoma (FL) who responded to induction treatment with rituximab plus chemotherapy.

TON - Daily

Use of adjuvant chemotherapy may need to be rethought for patients who experience a pathologic complete response (pCR) or with ypT3-4 residual tumor after neoadjuvant chemoradiation (CRT) for rectal cancer, according to a new analysis presented at the 2011 Gastrointestinal Cancers Symposium (Abstract 361).

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