Articles

Patients treated with bevacizumab for metastatic breast cancer (MBC) should be monitored closely for cardiotoxicity, according to a new meta-analysis, which showed an increased risk of congestive heart failure (CHF) in women treated with the vascular endothelial growth factor inhibitor compared with controls.
 
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Clinicians now have more evidence to support exercise recommendations for cancer patients and survivors.
 
A new study found that regular exercise—even 15 minutes per day—prolongs survival in men with prostate cancer. Other new research has shown that exercise reduces cancer-related fatigue among adult cancer survivors.
 
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Tablet splitting, a common practice in healthcare settings, results in wide dose deviations, which could have serious clinical consequences for tablets that have a narrow margin between therapeutic and toxic doses, a new study indicates.
 
The study, published in the January issue of the Journal of Advanced Nursing, showed that nearly a third of the split fragments deviated from recommended dosages by 15% or more.
 
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Adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with dexamethasone may have greater risk for neurocognitive impairment and poor emotional regulation than patients treated with prednisone, and they exhibited symptoms of physical stress. Read More ›

Almost half of the cancer patients in a recent study did not receive any thromboprophylaxis during hospitalization, even though cancer and its treatment increases the risk for deep-vein thrombosis (DVT) and pulmonary embolism (PE) and three professional organizations—the American College of Chest Physicians, the American Society of Clinical Oncology, and the National Comprehensive Cancer Network—have issued guidelines recommending DVT prophylaxis. Read More ›

SAN ANTONIO—Weightlifting can significantly reduce the likelihood that breast cancer patients will develop lymphedema after they complete treatment, according to results of the Physical Activity and Lymphedema trial reported at the 33rd annual San Antonio Breast Cancer Symposium. Read More ›

Clinicians should make decisions about prostate cancer treatment based on disease risk and life expectancy rather than chronologic age, according to University of California, San Francisco, researchers, who found that older men are more likely to have high-risk disease at diagnosis and less likely to receive potentially curative local therapy.
 
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ORLANDO—A study of physicians from five countries found that nurses and hematologists counseling patients with chronic myeloid leukemia about the importance of adherence to prescribed tyrosine kinase inhibitors (TKIs) or having an established adherence protocol, such as medication diaries, pill organizers, or informational calendars, was associated with improved adherence, and those patients who took the drugs as prescribed had significantly better therapeutic milestones. Read More ›

Two new studies suggest that use of vitamin supplements may reduce the risk of disease recurrence and mortality in women with breast cancer.
 
These studies contrast with some previous studies, which suggested that vitamin supplements, particularly antioxidants, may reduce the effectiveness of radiotherapy or chemotherapy.
 
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More patients with chronic myeloid leukemia (CML) in chronic phase achieve molecular response when peginterferon alfa-2a is added to imatinib therapy, but toxic side effects make completing treatment difficult for many, according to analysis of SPIRIT trial data (N Engl J Med. 2010;363:2511-2521). The researchers concluded that this increase in molecular responses could translate into better survival.
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