Articles

New Label for Oral Morphine Should Help Reduce Dose Errors

Roxane Laboratories and the US Food and Drug Administration (FDA) have notified healthcare professionals of serious adverse events and deaths resulting from accidental overdose of morphine sulfate oral solutions. In addition, the manufacturer has updated the product’s label to help prevent dosing errors.

TON - Daily

No new evidence yet shows the advantages of interstitial brachytherapy over other forms of treatment in men with localized prostate cancer, even though 20 new studies have been released, according to a report released today by the Institute for Quality and Efficiency in Health Care (IQWiG), a German independent scientific institute that investigates the benefits and harms of medical interventions. IQWiG, therefore, has not changed its conclusions from its 2007 report.

TON - Daily

The US Food and Drug Administration has approved a fentynal immediate-release transmucosal tablet (Abstral, ProStraken) for breakthrough cancer pain in adults, making it the only fast-acting lingual tablet on the US market. The tablet is indicated for those patients who already use opioid pain medication and can safely use high doses of an additional opioid medication.

TON - Daily

Patients treated with bevacizumab for metastatic breast cancer (MBC) should be monitored closely for cardiotoxicity, according to a new meta-analysis, which showed an increased risk of congestive heart failure (CHF) in women treated with the vascular endothelial growth factor inhibitor compared with controls.

TON - Daily

Clinicians now have more evidence to support exercise recommendations for cancer patients and survivors.

A new study found that regular exercise—even 15 minutes per day—prolongs survival in men with prostate cancer. Other new research has shown that exercise reduces cancer-related fatigue among adult cancer survivors.

TON - Daily

Tablet splitting, a common practice in healthcare settings, results in wide dose deviations, which could have serious clinical consequences for tablets that have a narrow margin between therapeutic and toxic doses, a new study indicates.

The study, published in the January issue of the Journal of Advanced Nursing, showed that nearly a third of the split fragments deviated from recommended dosages by 15% or more.

By Debra Wood

In the News

Web Exclusives

Adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with dexamethasone may have greater risk for neurocognitive impairment and poor emotional regulation than patients treated with prednisone, and they exhibited symptoms of physical stress. Read More ›

DVT Prophylaxis Underused for Cancer Patients

By Debra Wood

In the News

Web Exclusives

Almost half of the cancer patients in a recent study did not receive any thromboprophylaxis during hospitalization, even though cancer and its treatment increases the risk for deep-vein thrombosis (DVT) and pulmonary embolism (PE) and three professional organizations—the American College of Chest Physicians, the American Society of Clinical Oncology, and the National Comprehensive Cancer Network—have issued guidelines recommending DVT prophylaxis. Read More ›

Weightlifting Cuts Lymphedema Risk in Breast Cancer Patients

Web Exclusives

SAN ANTONIO—Weightlifting can significantly reduce the likelihood that breast cancer patients will develop lymphedema after they complete treatment, according to results of the Physical Activity and Lymphedema trial reported at the 33rd annual San Antonio Breast Cancer Symposium. Read More ›

Base Prostate Cancer Treatment on Risk, Life Expectancy Not Age, Researchers Say

TON - Daily

Clinicians should make decisions about prostate cancer treatment based on disease risk and life expectancy rather than chronologic age, according to University of California, San Francisco, researchers, who found that older men are more likely to have high-risk disease at diagnosis and less likely to receive potentially curative local therapy.

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