Articles

Adding chemotherapy to radiotherapy (RT) for muscle-invasive bladder cancer is well tolerated and improves loco-regional disease-free survival (LRDFS) compared with RT alone, according to a study presented at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO).
 
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The US Food and Drug Administration (FDA) has approved dasatinib (Sprycel, Bristol-Myers Squibb) 100 mg once daily for the treatment of adult patients with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phase.
 
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A study by Virginia Commonwealth University Massey Cancer Center researchers showed that most terminally ill cancer patients who were eligible for genetic testing did not receive it even though it could potentially save a relative's life.
 
The research, reported by John M. Quillin, PhD, and associates in the October issue of the Journal of Genetic Counseling, is the first to document the prevalence of hereditary cancer risk and the need for genetic services and patient education among terminally ill cancer patients.
 
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Patients with metastatic colorectal cancer (CRC) who have KRAS –mutated tumors are currently excluded from treatment with the antiepidermal growth factor monoclonal antibodies cetuximab and panitumumab. A new study, however, suggests that patients with a KRAS codon 13 mutation have better outcomes when treated with cetuximab than patients with other KRAS mutations.
 
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An updated clinical practice guideline issued by the American Society of Clinical Oncology and the American Society of Hematology provides detailed recommendations on use of the erythropoiesis-stimulating agents (ESAs) epoetin and darbepoetin in adults with cancer-induced anemia.
 
The guideline, which updates the 2007 guideline, states that these agents should be avoided in patients who are not receiving concurrent chemotherapy, except for those with lower-risk myelodysplastic syndromes.
 

Patient adherence to colorectal cancer (CRC) screening guidelines remains suboptimal, particularly among minorities. Two new studies suggest ways to increase screening rates.
 
One study, by Moshe Shike, MD, of Memorial Sloan-Kettering Cancer Center, New York, and associates found that offering CRC screening during mammography visits is “an effective way of generating interest and initiating the process” in minority women. The results are reported online in Cancer.
 
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CHICAGO—Among patients with lung cancer on highly emetogenic chemotherapy, those receiving palonosetron throughout all cycles of chemotherapy had a 31% lower risk of chemotherapy-induced nausea and vomiting (CINV) associated with an emergency department or hospital visit, than patients receiving other 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists (RAs).

The study was presented by Hind T. Hatoum, PhD, of the Center of Pharmacoeconomic Research at the University of Illinois at Chicago during the 46th annual meeting of the American Society of Clinical Oncology.

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The Doctor of Nursing Practice (DNP) degree has been designated by the American Association of Colleges of Nursing (AACN) as the graduate degree for advanced practice nurses (APNs). Currently, obtaining this degree remains an option; pursuit of a doctoral degree in nursing is a personal and professional decision made by some APNs. The trend toward doctoral preparation appears to be gaining momentum, however, and after the year 2015 it may be difficult to find a nurse practitioner program that awards a Master of Science in Nursing (MSN).

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SEATTLE—New doctors have received on-the-job training in residency programs for decades. Now, a growing number of new nurses are doing the exact same thing. Nurse residency programs are now rising in popularity and that, in part, is due to hospitals trying to stave off a huge projected nursing shortage over the next 10 to 15 years.

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CHICAGO—Targeted intraoperative radiotherapy (TIR) for breast cancer, in which radiotherapy is confined to the area of the breast where the tumor has been removed, has been found to be as good as whole breast radiotherapy at reducing breast cancer recurrence. Most important, the new data presented at the 46th annual meeting of the American Society of Clinical Oncology showed TIR can be carried out in just one hospital visit.

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