Articles

SAN DIEGO—Omitting adjuvant tamoxifen may not put women aged older than 65 years with early-stage breast cancer at increased risk for local or distant disease recurrence, according to a large, retrospective study presented at the 52nd annual meeting of the American Society for Radiation Oncology.

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MILAN—The investigative poly (ADPribose) polymerase (PARP) inhibitor iniparib (BSI-021) im proved not only progression-free survival (PFS) but also overall survival (OS) in the final analysis of a randomized phase 2 study, presented at the 35th European Society for Medical Oncology Congress by Joyce O’Shaughnessy, MD, of US Oncology and Baylor Sammons Cancer Center, Houston.

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SAN DIEGO—Elizabeth Brunton, RN, MSN, OCN, started in the nursing field in 1973. More than 35 years later, she is the recipient of the American Society for Radiation Oncology (ASTRO) Nurse Excellence Award. This award is presented annually to a registered nurse who goes above and beyond the normal standards of nursing practice.

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This past April, Geisinger Medical Center’s (GMC) Cancer Institute became one of 14 sites added to the National Cancer Institute Community Cancer Centers Program (NCCCP). Joining this national network of community cancer centers offers GMC the opportunity to expand its state-of-the-art cancer care and research in northeast Pennsylvania.

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Women with breast cancer who have elevated levels of C-peptide (a marker of insulin secretion) have significantly higher mortality rates than their peers with lower levels, results of the Health, Eating, Activity, and Lifestyle (HEAL) study indicate.
 
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Oral rivaroxaban’s efficacy at reducing the risk of recurrent venous thromboembolism (VTE) was confirmed in two trials presented at the annual meeting of the American Society of Hematology. The agent was studied for treatment of deep-vein thrombosis (DVT) as well as for continued therapy after initial anticoagulation treatment for DVT or pulmonary embolism.
 
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For patients with a past history or family history of colorectal cancer, annual fecal immunochemical tests (FITs) detect neoplasias sooner than scheduled 10-year colonoscopies, according to a new study published in the December issue of Gastroenterology. For patients with FIT-positive results, diagnosis was made sooner by 25 months for cancer and by 24 months for advanced adenomas.
 
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Researchers have confirmed the long-term benefits of adjuvant anastrozole to help stop recurrence of breast cancer in postmenopausal women with hormone-sensitive early breast cancer, according to a 10-year analysis of the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial published in The Lancet Oncology (Nov 16, 2010. Epub ahead of print).
 
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An adjuvant regimen of docetaxel, doxorubicin, and cyclophosphamide (TAC) is effective for women with high-risk, node-negative as well as node-positive breast cancer, according to a study by the Spanish Breast Cancer Research Group.
 
The taxane-based regimen has proved superior to fluorouracil, doxorubicin, and cyclophosphamide (FAC) in women with node-positive breast cancer, but its value in node-negative disease had not been determined.
 
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Exercise programs should be initiated more widely among established androgen-deprivation therapy (ADT) users, argue the results of a new study by researchers at the University of Toronto. In addition, their study highlights the importance of further investigation into whether initiating exercise at the same time as that of ADT can reverse or prevent the negative physical outcomes often associated with ADT.
 
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