Articles

This past April, Geisinger Medical Center’s (GMC) Cancer Institute became one of 14 sites added to the National Cancer Institute Community Cancer Centers Program (NCCCP). Joining this national network of community cancer centers offers GMC the opportunity to expand its state-of-the-art cancer care and research in northeast Pennsylvania.

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Women with breast cancer who have elevated levels of C-peptide (a marker of insulin secretion) have significantly higher mortality rates than their peers with lower levels, results of the Health, Eating, Activity, and Lifestyle (HEAL) study indicate.
 
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Oral rivaroxaban’s efficacy at reducing the risk of recurrent venous thromboembolism (VTE) was confirmed in two trials presented at the annual meeting of the American Society of Hematology. The agent was studied for treatment of deep-vein thrombosis (DVT) as well as for continued therapy after initial anticoagulation treatment for DVT or pulmonary embolism.
 
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For patients with a past history or family history of colorectal cancer, annual fecal immunochemical tests (FITs) detect neoplasias sooner than scheduled 10-year colonoscopies, according to a new study published in the December issue of Gastroenterology. For patients with FIT-positive results, diagnosis was made sooner by 25 months for cancer and by 24 months for advanced adenomas.
 
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Researchers have confirmed the long-term benefits of adjuvant anastrozole to help stop recurrence of breast cancer in postmenopausal women with hormone-sensitive early breast cancer, according to a 10-year analysis of the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial published in The Lancet Oncology (Nov 16, 2010. Epub ahead of print).
 
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An adjuvant regimen of docetaxel, doxorubicin, and cyclophosphamide (TAC) is effective for women with high-risk, node-negative as well as node-positive breast cancer, according to a study by the Spanish Breast Cancer Research Group.
 
The taxane-based regimen has proved superior to fluorouracil, doxorubicin, and cyclophosphamide (FAC) in women with node-positive breast cancer, but its value in node-negative disease had not been determined.
 
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Exercise programs should be initiated more widely among established androgen-deprivation therapy (ADT) users, argue the results of a new study by researchers at the University of Toronto. In addition, their study highlights the importance of further investigation into whether initiating exercise at the same time as that of ADT can reverse or prevent the negative physical outcomes often associated with ADT.
 
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Adjuvant trastuzumab treatment may be beneficial for women with small human epidermal growth factor receptor 2 (HER2)-positive breast tumors, according to a review by British researchers.
 
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Approximately half of colorectal and cervical cancer cases and one third of breast cancer cases are still diagnosed at a late stage of disease, according to a Surveillance Summary released by the US Centers for Disease Control and Prevention (CDC) in the November 26 issue of Morbidity and Mortality Weekly Report.
 
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Endosonography combined with surgical staging has greater sensitivity for detecting mediastinal nodal metastases, according to results of a randomized, controlled trial published in the November 24 issue of JAMA.
 
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