Articles

Surgery provides excellent long-term cancer control and high survival rates for men with aggressive prostate cancer, a new study suggests.
 
In the study by researchers from the Mayo Clinic, Rochester, Minnesota, and Fox Chase Cancer Center, Philadelphia, men with high-risk prostate cancer who underwent radical prostatectomy had a 10-year cancer-specific survival rate of 92% and an overall survival rate of 77%.
 
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Findings of a new study demonstrate the benefit of early referral of young women with breast cancer to reproductive specialists for fertility preservation.
 
The study, reported online September 27 in the Journal of Clinical Oncology, showed that referral to reproductive specialists before breast surgery increases the likelihood of obtaining a sufficient number of oocytes for fertility preservation without delaying breast cancer treatment.
 
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Findings of a large new study point to the potentially devastating impact of a cancer diagnosis on the mental health of a patient’s partner and the importance of involving family members in treatment.
 
The study of Danish men showed that men whose partners were diagnosed with breast cancer were significantly more likely to be hospitalized with an affective disorder than men whose partners did not have breast cancer. The results are reported in the September 27 online edition of Cancer.
 
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Women who have difficulty performing normal activities of daily living after an initial treatment for breast cancer have reduced overall survival compared with survivors without functional limitations, results of a long-term study indicate.
 
“Our study provides evidence of why it is important to develop interventions that improve physical function, to mitigate the adverse effects of physical limitations,” said lead author Dejana Braithwaite, PhD, of the University of California San Francisco.
 

Dexrazoxane provides long-term protection against against doxorubicin-induced heart damage in survivors of childhood high-risk acute lymphoblastic leukemia (ALL) and does not compromise oncologic efficacy, a new multicenter study indicates.
 
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Discontinuation of imatinib therapy puts patients with advanced gastrointestinal stromal tumors (GIST) at high risk for rapid disease progression and is not recommended unless substantial toxicity develops, according to French researchers.
 
After nearly 3 years of follow up, 2-year progression-free survival was 80% in patients who remained on imatinib but only 16% in those whose treatment was stopped.
 
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Regular consumption of three to four alcoholic drinks per week increases the risk of breast cancer recurrence and death from breast cancer, a study of breast cancer survivors suggests. Postmenopausal and overweight or obese women are at greatest risk.
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A man’s level of prostate specific antigen (PSA) at age 60 predicts his lifetime risk of metastasis and death from prostate cancer, a study of Swedish men indicates.
 
The findings, published online September 14 in BMJ, could be useful in determining which men should be screened for prostate cancer after the age of 60 and which may not benefit substantially from continued screening.
 
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In a case-control study, regular use of 75 mg/day of aspirin— lower than the standard 81-mg dose of baby aspirin—significantly reduced the risk of developing colorectal cancer (CRC). The effect was evident after 1 year and increased with longer use.
 
The findings of this large population-based study are applicable to the general population, not just high-risk patients, according to the authors.
 
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Patients with advanced cancer who die at home have greater quality of life (QOL) than patients who die in a hospital or intensive care unit. In addition, their caregivers experience less bereavement-related psychiatric illnesses, according to a study published online at the Journal of Clinical Oncology.
 
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