Articles

CHICAGO—A human monoclonal antibody that blocks a receptor that down regulates T-cell responses improves long-term survival in patients with previously treated advanced melanoma, according to the results of a phase 3 trial.

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SAN DIEGO—A program that calls for direct communication between interdisciplinary caregivers may help decrease falls in a hematology/oncology inpatient unit, according to data reported by Boston researchers.

Deborah O’Connor, RN, MS, CNML, at the Brigham and Women’s Hospital in Boston, and her colleagues presented the results of a falls prevention program that was “piloted” in a hematopoietic stem cell transplant (HSCT) unit at a tertiary academic teaching hospital.

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Bevacizumab (Avastin, Genentech) has been a popular first-line treatment for metastatic breast cancer since 2008, when the US Food and Drug Administration (FDA) granted special, fast-track approval for use in combination with paclitaxel. The accelerated approval was based on positive early findings from the E2100 trial, which showed that the addition of bevacizumab added 5.5 months of progression-free survival (PFS) over paclitaxel alone. Read More ›


healthy work environment is one in which people are valued and priority is given to the multiple aspects of the workplace that affect employees’ ability to function well in order to accomplish the goals of the organization.1 Since its early days, nursing has been a profession of service in a high-stress, ever-changing healthcare environment, often without appropriate thanks, reward, recognition, or appreciation. The psychological implication Read More ›


Adding two new biomarkers to a risk-prediction model allows enhanced identification of cancer patients at high or low risk of venous thromboembolism (VTE), according to a recent study published in Blood.
 
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The US Food and Drug Administration (FDA) has approved a higher, more efficacious dose of fulvestrant (Faslodex, AstraZeneca) injection for treatment of metastatic breast cancer. The newly approved dose of 500 mg replaces the previously approved monthly dose of 250 mg for the treatment of hormone receptor–positive (HR+) metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
 
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Deaths from ovarian cancer could drop by as much as 50% in the next 20 years if surgeons remove the fallopian tubes of women undergoing a hysterectomy or tubal ligation, according to a team of gynecologic oncologists from Vancouver General Hospital and the British Columbia Cancer Agency.
                                    
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This past April, Albert Einstein Cancer Center was selected to join the National Cancer Institute (NCI) Community Cancer Centers Program (NCCCP), which, in the words of William J. Tester, MD, FACP, medical director of Einstein’s Cancer Center, offers “an opportunity to bring more resources to our patients.”

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Multivitamin use during and after adjuvant chemotherapy did not reduce the risk of cancer recurrence or mortality in patients with stage III colon cancer, according to recently released findings of Cancer and Leukemia Group B (CALGB) 89803. Multivitamin use, however, also did not impact patients’ health negatively.
 
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Researchers have developed a tool for predicting individualized risk of local recurrence after breast-conserving surgery (BCS) in women with ductal carcinoma in situ (DCIS). The tool integrates 10 clinicopathologic variables to assist patients and their healthcare professionals decide among various treatment options with the goal of reducing over- and undertreatment of noninvasive breast cancer.
 
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